Evaluation of the therapeutic potential of resveratrol-loaded nanostructured lipid carriers on autosomal recessive spastic ataxia of Charlevoix-Saguenay patient-derived fibroblasts

Evaluation of the therapeutic potential of resveratrol-loaded nanostructured lipid carriers on autosomal recessive spastic ataxia of Charlevoix-Saguenay patient-derived fibroblasts

Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a neurological disease characterized by autosomal recessive mutations in the sacsin gene (SACS), that cause in patients progressive cerebellar atrophy, damage of the peripheral nerves, and cognitive impairment. No effective therap...

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Bibliographic Details
Main Authors: Özlem Şen, Melis Emanet, Attilio Marino, Melike Belenli Gümüş, Martina Bartolucci, Stefano Doccini, Federico Catalano, Giada Graziana Genchi, Filippo Maria Santorelli, Andrea Petretto, Gianni Ciofani
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Materials & Design
Subjects:
Resveratrol
ARSACS
Nanostructured lipid carriers
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127521005670

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http://www.sciencedirect.com/science/article/pii/S0264127521005670

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