Functional MAIT Cells Are Associated With Reduced Simian–Human Immunodeficiency Virus Infection

Functional MAIT Cells Are Associated With Reduced Simian–Human Immunodeficiency Virus Infection

Mucosa-associated invariant T (MAIT) cells are recently characterized as a novel subset of innate-like T cells that recognize microbial metabolites as presented by the MHC-1b-related protein MR1. The significance of MAIT cells in anti-bacterial defense is well-understood but not clear in viral infec...

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Bibliographic Details
Main Authors: Amudhan Murugesan, Chris Ibegbu, Tiffany M. Styles, Andrew T. Jones, Uma Shanmugasundaram, Pradeep B. J. Reddy, Sadia J. Rahman, Piu Saha, Matam Vijay-Kumar, Esaki Muthu Shankar, Rama Rao Amara, Vijayakumar Velu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Immunology
Subjects:
MAIT cells
HIV/SIV infection
CD8 T cells
rhesus macaques
innate like T cells
microbial metabolites
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.03053/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.03053/full

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