Investigating Spectrum of Biological Activity of 4- and 5-Chloro-2-hydroxy-N-[2-(arylamino)-1-alkyl-2-oxoethyl]benzamides

Investigating Spectrum of Biological Activity of 4- and 5-Chloro-2-hydroxy-N-[2-(arylamino)-1-alkyl-2-oxoethyl]benzamides

In this study, a series of twenty-two 5-chloro-2-hydroxy-N-[2-(arylamino)-1-alkyl-2-oxoethyl]benzamides and ten 4-chloro-2-hydroxy-N-[2-(arylamino)-1-alkyl-2-oxoethyl]benzamides is described. The compounds were analyzed using RP-HPLC to determine lipophilicity. Primary in vitro screening of the synt...

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Bibliographic Details
Main Authors: Jirina Stolarikova, Jarmila Vinsova, Marcela Vejsova, Katarina Kralova, Ales Imramovsky, Matus Pesko, Josef Jampilek
Format: Article
Language:English
Published: MDPI AG 2011-03-01
Series:Molecules
Subjects:
salicylanilide derivates
lipophilicity
in vitro antimycobacterial activity
in vitro antifungal activity
in vitro antibacterial activity
PET inhibition
spinach chloroplasts
structure–activity relationships
Online Access:http://www.mdpi.com/1420-3049/16/3/2414/

Internet

http://www.mdpi.com/1420-3049/16/3/2414/

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