Overexpression of the Promigratory and Prometastatic PTK7 Receptor Is Associated with an Adverse Clinical Outcome in Colorectal Cancer.

Biomarkers and novel therapeutic targets are urgently needed in colorectal cancer (CRC). The pseudo tyrosine kinase receptor 7 (PTK7) is involved in planar cell polarity and it is deregulated in various malignancies, including CRC. Yet, little is known about its protein expression in human CRC, or a...

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Main Authors: Anne-Catherine Lhoumeau, Sébastien Martinez, Jean-Marie Boher, Geneviève Monges, Rémy Castellano, Armelle Goubard, Marie Doremus, Flora Poizat, Bernard Lelong, Cécile de Chaisemartin, Florence Bardin, Patrice Viens, Jean-Luc Raoul, Thomas Prebet, Michel Aurrand-Lions, Jean-Paul Borg, Anthony Gonçalves
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4427440?pdf=render