Induction of erythropoiesis by hypoxia-inducible factor prolyl hydroxylase inhibitors without promotion of tumor initiation, progression, or metastasis in a VEGF-sensitive model of spontaneous breast cancer

Induction of erythropoiesis by hypoxia-inducible factor prolyl hydroxylase inhibitors without promotion of tumor initiation, progression, or metastasis in a VEGF-sensitive model of spontaneous breast cancer

Todd W Seeley, Mark D Sternlicht, Stephen J Klaus, Thomas B Neff, David Y Liu Therapeutics R&D, FibroGen, Inc., San Francisco, CA, USA Abstract: The effects of pharmacological hypoxia-inducible factor (HIF) stabilization were investigated in the MMTV-Neundl-YD5 (Ne...

Full description

Bibliographic Details
Main Authors: Seeley TW, Sternlicht MD, Klaus SJ, Neff TB, Liu DY
Format: Article
Language:English
Published: Dove Medical Press 2017-03-01
Series:Hypoxia
Subjects:
Cancer progression
erythropoiesis
hypoxia-inducible factor (HIF)
HIF prolyl hydroxylase inhibitors
vascular endothelial growth factor
MMTV-Neu breast cancer model
Online Access:https://www.dovepress.com/induction--of-erythropoiesis-by-hypoxia-inducible-factor-prolyl-hydrox-peer-reviewed-article-HP

Internet

https://www.dovepress.com/induction--of-erythropoiesis-by-hypoxia-inducible-factor-prolyl-hydrox-peer-reviewed-article-HP

Similar Items