Oxaloacetate Ameliorates Chemical Liver Injury via Oxidative Stress Reduction and Enhancement of Bioenergetic Fluxes

Oxaloacetate Ameliorates Chemical Liver Injury via Oxidative Stress Reduction and Enhancement of Bioenergetic Fluxes

Chemical injury is partly due to free radical lipid peroxidation, which can induce oxidative stress and produce a large number of reactive oxygen species (ROS). Oxaloacetic acid is an important intermediary in the tricarboxylic acid cycle (TCA cycle) and participates in metabolism and energy product...

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Bibliographic Details
Main Authors: Ye Kuang, Xiaoyun Han, Mu Xu, Yue Wang, Yuxiang Zhao, Qing Yang
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:International Journal of Molecular Sciences
Subjects:
oxaloacetate
hydrogen peroxide
carbon tetrachloride
metabolism
hepatoprotection
Online Access:http://www.mdpi.com/1422-0067/19/6/1626

Internet

http://www.mdpi.com/1422-0067/19/6/1626

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