Norepinephrine Induces PTSD-Like Memory Impairments via Regulation of the β-Adrenoceptor-cAMP/PKA and CaMK II/PKC Systems in the Basolateral Amygdala

Norepinephrine Induces PTSD-Like Memory Impairments via Regulation of the β-Adrenoceptor-cAMP/PKA and CaMK II/PKC Systems in the Basolateral Amygdala

Glucocorticoids (GCs) can modulate the memory enhancement process during stressful events, and this modulation requires arousal-induced norepinephrine (NE) activation in the basolateral amygdale (BLA). Our previous study found that an intrahippocampal infusion of propranolol dose-dependently induced...

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Bibliographic Details
Main Authors: Xiang-Hui Liu, Rong-Ting Zhu, Bo Hao, Yan-Wei Shi, Xiao-Guang Wang, Li Xue, Hu Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
PTSD
fear conditioning
basolateral amygdala
norepinephrine
AMPA
cAMP/PKA
Online Access:https://www.frontiersin.org/article/10.3389/fnbeh.2019.00043/full

Internet

https://www.frontiersin.org/article/10.3389/fnbeh.2019.00043/full

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