Decay kinetics of an interferon gamma release assay with anti-tuberculosis therapy in newly diagnosed tuberculosis cases.

Qualitative and quantitative changes in IGRA response offer promise as biomarkers to monitor Tuberculosis (TB) drug therapy, and for the comparison of new interventions. We studied the decay kinetics of TB-specific antigen T-cell responses measured with an in-house ELISPOT assay during the course of...

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Bibliographic Details
Main Authors: Ifedayo M O Adetifa, Martin O C Ota, Brigitte Walther, Abdulrahman S Hammond, Moses D Lugos, David J Jeffries, Simon A Donkor, Richard A Adegbola, Philip C Hill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2931700?pdf=render