Directed movement toward, translocation along, penetration into and exit from vascular networks by breast cancer cells in 3D

Directed movement toward, translocation along, penetration into and exit from vascular networks by breast cancer cells in 3D

We developed a computer-assisted platform using laser scanning confocal microscopy to 3D reconstruct in real-time interactions between metastatic breast cancer cells and human umbilical vein endothelial cells (HUVECs). We demonstrate that MB-231 cancer cells migrate toward HUVEC networks, facilitate...

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Bibliographic Details
Main Authors: Deborah J. Wessels, Claude Pujol, Nikash Pradhan, Daniel F. Lusche, Luis Gonzalez, Sydney E. Kelly, Elizabeth M. Martin, Edward R. Voss, Yang-Nim Park, Michael Dailey, Sonia L. Sugg, Sneha Phadke, Amani Bashir, David R. Soll
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Cell Adhesion & Migration
Subjects:
filopodia
pseudopod
intravasation
extravasation
computer-assisted reconstruction
cd44
rhamm
Online Access:http://dx.doi.org/10.1080/19336918.2021.1957527

Internet

http://dx.doi.org/10.1080/19336918.2021.1957527

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