Membrane Sealant Poloxamer P188 Protects Against Isoproterenol Induced Cardiomyopathy in Dystrophin Deficient Mice

Membrane Sealant Poloxamer P188 Protects Against Isoproterenol Induced Cardiomyopathy in Dystrophin Deficient Mice

<p>Abstract</p> <p>Background</p> <p>Cardiomyopathy in Duchenne muscular dystrophy (DMD) is an increasing cause of death in patients. The absence of dystrophin leads to loss of membrane integrity, cell death and fibrosis in cardiac muscle. Treatment of cardiomyocyte mem...

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Bibliographic Details
Main Authors: Sali Arpana, Yu Qing, Guerron Alfredo D, Spurney Christopher F, van der Meulen Jack H, Hoffman Eric P, Nagaraju Kanneboyina
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Cardiovascular Disorders
Subjects:
Duchenne muscular dystrophy
mdx
poloxamer
cardiomyopathy
isoproterenol
Online Access:http://www.biomedcentral.com/1471-2261/11/20

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http://www.biomedcentral.com/1471-2261/11/20

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