LAG3 is not expressed in human and murine neurons and does not modulate α‐synucleinopathies

LAG3 is not expressed in human and murine neurons and does not modulate α‐synucleinopathies

Abstract While the initial pathology of Parkinson’s disease and other α‐synucleinopathies is often confined to circumscribed brain regions, it can spread and progressively affect adjacent and distant brain locales. This process may be controlled by cellular receptors of α‐synuclein fibrils, one of w...

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Bibliographic Details
Main Authors: Marc Emmenegger, Elena De Cecco, Marian Hruska‐Plochan, Timo Eninger, Matthias M Schneider, Melanie Barth, Elena Tantardini, Pierre de Rossi, Mehtap Bacioglu, Rebekah G Langston, Alice Kaganovich, Nora Bengoa‐Vergniory, Andrès Gonzalez‐Guerra, Merve Avar, Daniel Heinzer, Regina Reimann, Lisa M Häsler, Therese W Herling, Naunehal S Matharu, Natalie Landeck, Kelvin Luk, Ronald Melki, Philipp J Kahle, Simone Hornemann, Tuomas P J Knowles, Mark R Cookson, Magdalini Polymenidou, Mathias Jucker, Adriano Aguzzi
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:EMBO Molecular Medicine
Subjects:
LAG3
neurodegeneration
prionoids
α‐synuclein
Online Access:https://doi.org/10.15252/emmm.202114745

Internet

https://doi.org/10.15252/emmm.202114745

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