Enhanced Delivery and Potency of Self-Amplifying mRNA Vaccines by Electroporation in Situ

Enhanced Delivery and Potency of Self-Amplifying mRNA Vaccines by Electroporation in Situ

Nucleic acid-based vaccines such as viral vectors, plasmid DNA (pDNA), and mRNA are being developed as a means to address limitations of both live-attenuated and subunit vaccines. DNA vaccines have been shown to be potent in a wide variety of animal species and several products are now licensed for...

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Bibliographic Details
Main Authors: Kaustuv Banerjee, Julie Hickman, Andrew Geall, Jeffrey B. Ulmer, Gleb Kichaev, Niranjan Y. Sardesai, Yen Cu, Susan Barnett, Gillis Otten, Kate E. Broderick
Format: Article
Language:English
Published: MDPI AG 2013-08-01
Series:Vaccines
Subjects:
antibodies
T cell responses
vaccine
HIV
Online Access:http://www.mdpi.com/2076-393X/1/3/367

Internet

http://www.mdpi.com/2076-393X/1/3/367

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