Antiplasmodial dihetarylthioethers target the coenzyme A synthesis pathway in Plasmodium falciparum erythrocytic stages

Antiplasmodial dihetarylthioethers target the coenzyme A synthesis pathway in Plasmodium falciparum erythrocytic stages

Abstract Background Malaria is a widespread infectious disease that threatens a large proportion of the population in tropical and subtropical areas. Given the emerging resistance against the current standard anti-malaria chemotherapeutics, the development of alternative drugs is urgently needed. Ne...

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Bibliographic Details
Main Authors: Thomas Weidner, Leonardo Lucantoni, Abed Nasereddin, Lutz Preu, Peter G. Jones, Ron Dzikowski, Vicky M. Avery, Conrad Kunick
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Malaria Journal
Subjects:
Anti-malaria drugs
Coenzyme A synthesis
Drug discovery
Malaria
1,3,4-Oxadiazole
Oxazole
Online Access:http://link.springer.com/article/10.1186/s12936-017-1839-3

Internet

http://link.springer.com/article/10.1186/s12936-017-1839-3

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