Host alternation is necessary to maintain the genome stability of rift valley fever virus.

BACKGROUND: Most arthropod-borne viruses (arboviruses) are RNA viruses, which are maintained in nature by replication cycles that alternate between arthropod and vertebrate hosts. Arboviruses appear to experience lower rates of evolution than RNA viruses that replicate in a single host. This genetic...

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Bibliographic Details
Main Authors: Sara Moutailler, Benjamin Roche, Jean-Michel Thiberge, Valérie Caro, François Rougeon, Anna-Bella Failloux
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3101185?pdf=render