Markov Chain-Based Sampling for Exploring RNA Secondary Structure under the Nearest Neighbor Thermodynamic Model and Extended Applications

Ribonucleic acid (RNA) secondary structures and branching properties are important for determining functional ramifications in biology. While energy minimization of the Nearest Neighbor Thermodynamic Model (NNTM) is commonly used to identify such properties (number of hairpins, maximum ladder distan...

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Bibliographic Details
Main Authors: Anna Kirkpatrick, Kalen Patton, Prasad Tetali, Cassie Mitchell
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Mathematical and Computational Applications
Subjects:
Online Access:https://www.mdpi.com/2297-8747/25/4/67