Ability of the new AT receptor blocker azilsartan to block angiotensin II-induced AT receptor activation after wash-out

Introduction: The recently approved angiotensin II (Ang II) type 1 (AT 1 ) receptor blocker (ARB) azilsartan strongly reduces blood pressure (BP) in patients with hypertension. We previously reported that azilsartan showed unique binding behavior to the AT 1 receptor because of its 5-oxo-1,2,4-oxadi...

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Bibliographic Details
Main Authors: Shin-ichiro Miura, Yoshino Matsuo, Asuka Nakayama, Sayo Tomita, Yasunori Suematsu, Keijiro Saku
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2014-03-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320313482170