Overexpression of MEOX2 and TWIST1 is associated with H3K27me3 levels and determines lung cancer chemoresistance and prognosis.

Overexpression of MEOX2 and TWIST1 is associated with H3K27me3 levels and determines lung cancer chemoresistance and prognosis.

Lung cancer is the leading cause of death from malignant diseases worldwide, with the non-small cell (NSCLC) subtype accounting for the majority of cases. NSCLC is characterized by frequent genomic imbalances and copy number variations (CNVs), but the epigenetic aberrations that are associated with...

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Main Authors: Federico Ávila-Moreno, Leonel Armas-López, Aldo M Álvarez-Moran, Zoila López-Bujanda, Blanca Ortiz-Quintero, Alfredo Hidalgo-Miranda, Francisco Urrea-Ramírez, R María Rivera-Rosales, Eugenia Vázquez-Manríquez, Erika Peña-Mirabal, José Morales-Gómez, Juan C Vázquez-Minero, José L Téllez-Becerra, Roberto Ramírez-Mendoza, Alejandro Ávalos-Bracho, Enrique Guzmán de Alba, Karla Vázquez-Santillán, Vilma Maldonado-Lagunas, Patricio Santillán-Doherty, Patricia Piña-Sánchez, Joaquin Zúñiga-Ramos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4252097?pdf=render

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http://europepmc.org/articles/PMC4252097?pdf=render

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