Significance of MEF2C and RUNX3 Regulation for Endochondral Differentiation of Human Mesenchymal Progenitor Cells

Guiding progenitor cell development between chondral versus endochondral pathways is still an unachieved task of cartilage neogenesis, and human mesenchymal progenitor cell (MPC) chondrogenesis is considered as a valuable model to better understand hypertrophic development of chondrocytes. Transcrip...

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Bibliographic Details
Main Authors: Simon I. Dreher, Jennifer Fischer, Tilman Walker, Solvig Diederichs, Wiltrud Richter
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
FGF
WNT
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00081/full