Immunological and translational aspects of NK cell-based anti-tumor immunotherapies
Natural killer (NK) cells play a pivotal role in the first line of defence against cancer. NK cells that are deficient in CD3 and a clonal T cell receptor (TCR) can be subdivided into two major subtypes, CD56dimCD16+ cytotoxic and CD56brightCD16- immunoregulatory NK cells. Cytotoxic NK cells directl...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2016-11-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00492/full |