The role of HPV16 regulatory region methylation in viral oncogenes E6 and E7 eхpression in primary cervical cancer lesions
Background. Overexpression of the human papillomavirus oncogenes E6 and E7 is a major factor in initiation and progression of HPV-induced tumors. Inactivation of negative regulatory function of E2 protein – the main viral transcription and replication regulator – is considered to be an important mec...
Main Authors: | , , , , , |
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Format: | Article |
Language: | Russian |
Published: |
ABV-press
2019-01-01
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Series: | Uspehi Molekulârnoj Onkologii |
Subjects: | |
Online Access: | https://umo.abvpress.ru/jour/article/view/180 |