Notch/Wnt cross-signalling regulates stemness of dental pulp stem cells through expression of neural crest and core pluripotency factors

Notch/Wnt cross-signalling regulates stemness of dental pulp stem cells through expression of neural crest and core pluripotency factors

Dental pulp stem cells (DPSCs) from adult teeth express neural crest (NC) markers together with core transcriptional factors associated with stem cell pluripotency, such as Oct4a, Sox2, c-Myc, Rex1, Stella/Dppa3, Ssea1/Fut4, Lin28 and Nanog. The possibility to boost the natural stemness features of...

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Bibliographic Details
Main Authors: V Uribe-Etxebarria, J Luzuriaga, P García-Gallastegui, A Agliano, F Unda, G Ibarretxe
Format: Article
Language:English
Published: AO Research Institute Davos 2017-11-01
Series:European Cells & Materials
Subjects:
Dental pulp stem cells
multipotency
self-renewal
pluripotency core factors
neural crest
stemness and differentiation
osteogenesis
adipogenesis
Notch
Wnt
BIO
DAPT
Wnt-3a
Online Access:http://www.ecmjournal.org/papers/vol034/pdf/v034a16.pdf

Internet

http://www.ecmjournal.org/papers/vol034/pdf/v034a16.pdf

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