IFITM3 inhibits influenza A virus infection by preventing cytosolic entry.

IFITM3 inhibits influenza A virus infection by preventing cytosolic entry.

To replicate, viruses must gain access to the host cell's resources. Interferon (IFN) regulates the actions of a large complement of interferon effector genes (IEGs) that prevent viral replication. The interferon inducible transmembrane protein family members, IFITM1, 2 and 3, are IEGs required...

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Bibliographic Details
Main Authors: Eric M Feeley, Jennifer S Sims, Sinu P John, Christopher R Chin, Thomas Pertel, Li-Mei Chen, Gaurav D Gaiha, Bethany J Ryan, Ruben O Donis, Stephen J Elledge, Abraham L Brass
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-10-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22046135/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22046135/?tool=EBI

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