Pharmacokinetics of Sublingual Buprenorphine Tablets Following Single and Multiple Doses in Chinese Participants With and Without Opioid Use Disorder

Pharmacokinetics of Sublingual Buprenorphine Tablets Following Single and Multiple Doses in Chinese Participants With and Without Opioid Use Disorder

Abstract Background Two phase I studies assessed the pharmacokinetics of buprenorphine, its metabolite norbuprenorphine, and naloxone following administration of buprenorphine/naloxone sublingual tablets in Chinese participants. Methods In the first phase I, open-label, single ascending-dose (SAD) s...

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Bibliographic Details
Main Authors: Ruihua Dong, Hongyun Wang, Dandan Li, Liwei Lang, Frank Gray, Yongzhen Liu, Celine M. Laffont, Malcolm Young, Ji Jiang, Zeyuan Liu, Susan M. Learned
Format: Article
Language:English
Published: Adis, Springer Healthcare 2019-06-01
Series:Drugs in R&D
Online Access:http://link.springer.com/article/10.1007/s40268-019-0277-9

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http://link.springer.com/article/10.1007/s40268-019-0277-9

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