Identification of Androgen Receptor Splice Variants in the Pten Deficient Murine Prostate Cancer Model.

Identification of Androgen Receptor Splice Variants in the Pten Deficient Murine Prostate Cancer Model.

Androgen receptor (AR) variants are associated with resistance to anti androgen therapy both in human prostate cancer cell lines and clinical samples. These observations support the hypothesis that AR isoform accumulation is a consequence of selective therapeutic pressure on the full length AR. The...

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Bibliographic Details
Main Authors: Mengmeng Liang, Helty Adisetiyo, Xiuqing Li, Ren Liu, Parkash Gill, Pradip Roy-Burman, Jeremy O Jones, David J Mulholland
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4510390?pdf=render

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http://europepmc.org/articles/PMC4510390?pdf=render

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