Loss of Selenov predisposes mice to extra fat accumulation and attenuated energy expenditure

Loss of Selenov predisposes mice to extra fat accumulation and attenuated energy expenditure

Selenoprotein V (SELENOV) is a new and the least conserved member of the selenoprotein family. Herein we generated Selenov knockout (KO) mice to determine its in vivo function. The KO led to 16–19% increases (P < 0.05) in body weight that were largely due to 54% higher (P < 0.05) fat mass accu...

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Bibliographic Details
Main Authors: Ling-Li Chen, Jia-Qiang Huang, Yuan-Yuan Wu, Liang-Bing Chen, Shu-Ping Li, Xu Zhang, Sen Wu, Fa-Zheng Ren, Xin-Gen Lei
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Redox Biology
Subjects:
Body weight
Energy balance
High-fat diet
Lipid metabolism
O-GlcNAcylation
Selenoprotein
Online Access:http://www.sciencedirect.com/science/article/pii/S221323172100207X

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http://www.sciencedirect.com/science/article/pii/S221323172100207X

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