Valproic Acid-Induced Hepatotoxicity and the Protective Role of Thiol Reductants

Valproic Acid-Induced Hepatotoxicity and the Protective Role of Thiol Reductants

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<p>Valproic acid (VPA) is a widely administered drug against epilepsy and several other neurological disorders. On the other hand, liver injury is a deleterious side effect associated with VPA. Oxidative stress seems to play a critical role in VPA-induced hepatotoxicity. The current investigat...

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Bibliographic Details
Main Authors: Nahid Najafi, Akram Jamshidzadeh, Hamideh Fallahzadeh, Mahmoud Omidi, Narges Abdoli, Asma Najibi, Negar Azarpira, Reza Heidari, Hossein Niknahad
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2017-05-01
Series:Trends in Pharmaceutical Sciences
Subjects:
Glutathione
Hepatoprotective
Hepatotoxicity
Oxidative stress
Sodium valproate
Online Access:http://tips.sums.ac.ir/index.php/TiPS/article/view/122

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http://tips.sums.ac.ir/index.php/TiPS/article/view/122

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