Transcriptional and immunological analysis of the putative outer membrane protein and vaccine candidate TprL of Treponema pallidum.

<h4>Background</h4>An effective syphilis vaccine should elicit antibodies to Treponema pallidum subsp. pallidum (T. p. pallidum) surface antigens to induce pathogen clearance through opsonophagocytosis. Although the combination of bioinformatics, structural, and functional analyses of T....

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Bibliographic Details
Main Authors: Austin M Haynes, Mark Fernandez, Emily Romeis, Oriol Mitjà, Kelika A Konda, Silver K Vargas, Maria Eguiluz, Carlos F Caceres, Jeffrey D Klausner, Lorenzo Giacani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008812