A histone-like protein of mycobacteria possesses ferritin superfamily protein-like activity and protects against DNA damage by Fenton reaction.

A histone-like protein of mycobacteria possesses ferritin superfamily protein-like activity and protects against DNA damage by Fenton reaction.

Iron is an essential metal for living organisms but its level must be strictly controlled in cells, because ferrous ion induces toxicity by generating highly active reactive oxygen, hydroxyl radicals, through the Fenton reaction. In addition, ferric ion shows low solubility under physiological condi...

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Bibliographic Details
Main Authors: Masaki Takatsuka, Mayuko Osada-Oka, Eisuke F Satoh, Kengo Kitadokoro, Yukiko Nishiuchi, Mamiko Niki, Masayasu Inoue, Kazuhiro Iwai, Tetsuo Arakawa, Yoshihiro Shimoji, Hisashi Ogura, Kazuo Kobayashi, Anura Rambukkana, Sohkichi Matsumoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3116847?pdf=render

Internet

http://europepmc.org/articles/PMC3116847?pdf=render

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