Combined effect of metformin and gallic acid on inflammation, antioxidant status, endoplasmic reticulum (ER) stress and glucose metabolism in fructose-fed streptozotocin-induced diabetic rats

Over time, diabetes patients usually need combination therapy involving two or more agents, including phytonutrients to attain therapeutic targets. The purpose of this research is to elucidate the combined effect of metformin and gallic acid (GA) on glucose metabolism, inflammation as well as oxidat...

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Bibliographic Details
Main Authors: Tajudeen O. Obafemi, Kikelomo F. Jaiyesimi, Adenike A. Olomola, Oluwaseun R. Olasehinde, Oyindamola A. Olaoye, Funmilayo D. Adewumi, Blessing A. Afolabi, Olusola B. Adewale, Christopher O. Akintayo, Oluwafemi A. Ojo
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Toxicology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750021001384