Inhibitory activity of the isoflavone biochanin A on intracellular bacteria of genus Chlamydia and initial development of a buccal formulation.

Given the established role of Chlamydia spp. as causative agents of both acute and chronic diseases, search for new antimicrobial agents against these intracellular bacteria is required to promote human health. Isoflavones are naturally occurring phytoestrogens, antioxidants and efflux pump inhibito...

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Main Authors: Leena Hanski, Natalja Genina, Hanna Uvell, Kristina Malinovskaja, Åsa Gylfe, Timo Laaksonen, Ruzica Kolakovic, Ermei Mäkilä, Jarno Salonen, Jouni Hirvonen, Mikael Elofsson, Niklas Sandler, Pia M Vuorela
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4267780?pdf=render