Drug Tolerant Anti-drug Antibody Assay for Infliximab Treatment in Clinical Practice Identifies Positive Cases Earlier

Drug Tolerant Anti-drug Antibody Assay for Infliximab Treatment in Clinical Practice Identifies Positive Cases Earlier

A subgroup of patients treated with infliximab lose response to the treatment and one reason for this is the development of anti-drug antibodies (ADA). If used optimally, measuring drug and ADA level could lead to a more personalized and efficient treatment regime, and enable identification of ADA-p...

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Bibliographic Details
Main Authors: Nastya Kharlamova, Christina Hermanrud, Nicky Dunn, Malin Ryner, Karen Hambardzumyan, Nancy Vivar Pomiano, Per Marits, Inger Gjertsson, Saedis Saevarsdottir, Rille Pullerits, Anna Fogdell-Hahn
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
anti-drug antibody
serum infliximab
clinical threshold value
clinical effect
PandA
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01365/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01365/full

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