Development of a hexavalent recombinant protein vaccine adjuvanted with Montanide ISA 50 V and determination of its protective efficacy against acute toxoplasmosis

Abstract Background Toxoplasma gondii is an obligate intracellular parasite that can infect almost all warm-blooded animals, avian species and humans. Toxoplasmosis is asymptomatic in healthy individuals, whereas it may lead to death in immune suppressed or deficient patients. A vaccine against T. g...

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Main Authors: Esra Atalay Şahar, Hüseyin Can, Sultan Gülçe İz, Aysu Değirmenci Döşkaya, Mina Kalantari-Dehaghi, Remziye Deveci, Adnan Yüksel Gürüz, Mert Döşkaya
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Infectious Diseases
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12879-020-05220-2