Coupling Langevin Dynamics With Continuum Mechanics: Exposing the Role of Sarcomere Stretch Activation Mechanisms to Cardiac Function

High-performance computing approaches that combine molecular-scale and macroscale continuum mechanics have long been anticipated in various fields. Such approaches may enrich our understanding of the links between microscale molecular mechanisms and macroscopic properties in the continuum. However,...

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Bibliographic Details
Main Authors: Takumi Washio, Seiryo Sugiura, Ryo Kanada, Jun-Ichi Okada, Toshiaki Hisada
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2018.00333/full