Inhibitory effects of pesticides on proteasome activity: Implication in Parkinson's disease

Inhibitory effects of pesticides on proteasome activity: Implication in Parkinson's disease

Epidemiological studies have suggested a correlation of pesticides and Parkinson's disease (PD) while genetic and biochemical studies have implicated the ubiquitin–proteasome system (UPS) in the pathogenesis of PD. In the present studies, we tested the hypothesis that pesticide exposure increas...

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Bibliographic Details
Main Authors: Xue-Feng Wang, Sharon Li, Arthur P. Chou, Jeff M. Bronstein
Format: Article
Language:English
Published: Elsevier 2006-07-01
Series:Neurobiology of Disease
Subjects:
Parkinson's disease
Ubiquitin–proteasome system
Pesticides
Environmental toxin
Neurotoxicity
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106000556

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http://www.sciencedirect.com/science/article/pii/S0969996106000556

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