The Role of the Cyclin Dependent Kinase Inhibitor p21<sup>cip1/waf1</sup> in Targeting Cancer: Molecular Mechanisms and Novel Therapeutics
p21<b><sup>cip1/waf1</sup></b> mediates various biological activities by sensing and responding to multiple stimuli, via p53-dependent and independent pathways. p21 is known to act as a tumor suppressor mainly by inhibiting cell cycle progression and allowing DNA repair. Sign...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-09-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/11/10/1475 |