Ranking the Predictive Power of Clinical and Biological Features Associated With Disease Progression in Huntington's Disease

Ranking the Predictive Power of Clinical and Biological Features Associated With Disease Progression in Huntington's Disease

Huntington's disease (HD) is characterised by a triad of cognitive, behavioural, and motor symptoms which lead to functional decline and loss of independence. With potential disease-modifying therapies in development, there is interest in accurately measuring HD progression and characterising p...

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Bibliographic Details
Main Authors: Naghmeh Ghazaleh, Richard Houghton, Giuseppe Palermo, Scott A. Schobel, Peter A. Wijeratne, Jeffrey D. Long
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Neurology
Subjects:
Huntington's disease
disease progression
prognostic variables
machine learning
random forest
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.678484/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2021.678484/full

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