Weakening of resistance force by cell–ECM interactions regulate cell migration directionality and pattern formation
Hagiwara et al. investigate how spatio-temporally remodeled ECM alters the resistance force exerted on cells using microfabrication techniques, optical tweezers and mathematical models. The authors demonstrate that active remodeling of the microenvironment modulates force exerted on cells by the ECM...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2021-06-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-021-02350-4 |