Development of a Quantitative One-Step RT-PCR Method for the Detection of Sabin 2 Virus Contamination in a Novel Oral Poliovirus Vaccine Type 2

Development of a Quantitative One-Step RT-PCR Method for the Detection of Sabin 2 Virus Contamination in a Novel Oral Poliovirus Vaccine Type 2

To control circulating vaccine-derived type 2 poliovirus outbreaks, a more genetically stable novel Oral Poliovirus Vaccine type 2 (nOPV2) was developed by targeted modifications of Sabin 2 genome. Since the use of OPV2 made of Sabin 2 strain has been stopped, it is important to exclude the possibil...

Full description

Bibliographic Details
Main Authors: Hasmik Manukyan, Erman Tritama, Rahnuma Wahid, Azeem Ansari, John Konz, Konstantin Chumakov, Majid Laassri
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Vaccines
Subjects:
release test
quality control
OPV
nOPV
Sabin 2 virus contaminant
Online Access:https://www.mdpi.com/2076-393X/9/7/688

Similar Items

Similar Items