Antimonial drugs entrapped into phosphatidylserine liposomes: physicochemical evaluation and antileishmanial activity

Antimonial drugs entrapped into phosphatidylserine liposomes: physicochemical evaluation and antileishmanial activity

Abstract: INTRODUCTION: Leishmaniasis is a disease caused by the protozoan Leishmania that resides mainly in mononuclear phagocytic system tissues. Pentavalent antimonials are the main treatment option, although these drugs have toxic side effects and high resistance rates. A potentially alternati...

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Bibliographic Details
Main Authors: Samanta Etel Treiger Borborema, João Alberto Osso Junior, Heitor Franco de Andrade Junior, Nanci do Nascimento
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2016-04-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Antimony
Leishmania infantum
Liposome
Meglumine antimoniate
Phosphatidylserine
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822016000200196&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822016000200196&lng=en&tlng=en

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