Salvinorin A reduces mechanical allodynia and spinal neuronal hyperexcitability induced by peripheral formalin injection

Salvinorin A reduces mechanical allodynia and spinal neuronal hyperexcitability induced by peripheral formalin injection

<p>Abstract</p> <p>Background</p> <p>Salvinorin A (SA), the main active component of <it>Salvia Divinorum,</it> is a non-nitrogenous kappa opioid receptor (KOR) agonist. It has been shown to reduce acute pain and to exert potent antinflammatory effects. This...

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Bibliographic Details
Main Authors: Guida Francesca, Luongo Livio, Aviello Gabriella, Palazzo Enza, De Chiaro Maria, Gatta Luisa, Boccella Serena, Marabese Ida, Zjawiony Jordan K, Capasso Raffaele, Izzo Angelo A, de Novellis Vito, Maione Sabatino
Format: Article
Language:English
Published: SAGE Publishing 2012-08-01
Series:Molecular Pain
Subjects:
Salvinorin A
Formalin injection
Allodynia
Nociceptive spinal neurons
Glial cells
Online Access:http://www.molecularpain.com/content/8/1/60

Internet

http://www.molecularpain.com/content/8/1/60

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