Changes of KEAP1/NRF2 and IKB/NF-κB Expression Levels Induced by Cell-Free DNA in Different Cell Types

Changes of KEAP1/NRF2 and IKB/NF-κB Expression Levels Induced by Cell-Free DNA in Different Cell Types

Cell-free DNA (cfDNA) is a circulating DNA of nuclear and mitochondrial origin mainly derived from dying cells. Recent studies have shown that cfDNA is a stress signaling DAMP (damage-associated molecular pattern) molecule. We report here that the expression profiles of cfDNA-induced factors NRF2 an...

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Bibliographic Details
Main Authors: Svetlana V. Kostyuk, Lev N. Porokhovnik, Elizaveta S. Ershova, Elena M. Malinovskaya, Marina S. Konkova, Larisa V. Kameneva, Olga A. Dolgikh, Vladimir P. Veiko, Vladimir M. Pisarev, Andrew V. Martynov, Vasilina A. Sergeeva, Andrew A. Kaliyanov, Anton D. Filev, Julia M. Chudakova, Margarita S. Abramova, Serguey I. Kutsev, Vera L. Izhevskaya, Nataliya N. Veiko
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/1052413

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http://dx.doi.org/10.1155/2018/1052413

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