Poly-ε-caprolactone microspheres containing interferon alpha as alternative formulations for the treatment of chronic hepatitis C

Interferon-alpha (IFN-alpha) is one of the main drugs used in the treatment of hepatitis C. Use of IFN-alpha has some limitations that result in poor treatment efficacy and low patient compliance. Therefore, the aim of this study was to develop poly-ε-caprolactone (PCL) microspheres contain...

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Bibliographic Details
Main Authors: Cristiane da Silva Melo, Bruno Gonçalves Pereira, Armando Silva-Cunha, Sílvia Ligório Fialho
Format: Article
Language:English
Published: Universidade de São Paulo 2012-03-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000100006