Validation of a Loop-Mediated Isothermal Amplification Assay for Rapid Diagnosis of Invasive Pneumococcal Disease

Validation of a Loop-Mediated Isothermal Amplification Assay for Rapid Diagnosis of Invasive Pneumococcal Disease

Current molecular PCR-based techniques used for detecting Streptococcus pneumoniae, the causative pathogen of invasive pneumococcal disease (IPD), are accurate but have a run time of several hours. We aimed to develop and validate a novel real-time loop mediated amplification (LAMP) assay for rapid...

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Bibliographic Details
Main Authors: Héctor David de Paz, Pedro Brotons, Cristina Esteva, Carmen Muñoz-Almagro
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Streptococcus pneumoniae
loop-mediated isothermal amplification
invasive pneumococcal disease
rapid diagnosis
diagnostic accuracy
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00115/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2020.00115/full

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