Invaders Exposed: Understanding and Targeting Tumor Cell Invasion in Diffuse Intrinsic Pontine Glioma

Invaders Exposed: Understanding and Targeting Tumor Cell Invasion in Diffuse Intrinsic Pontine Glioma

Diffuse Intrinsic Pontine Glioma (DIPG) is a rare, highly aggressive pediatric brain tumor that originates in the pons. DIPG is untreatable and universally fatal, with a median life expectancy of less than a year. Resection is not an option, due to the anatomical location of the tumor, radiotherapy...

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Bibliographic Details
Main Authors: T. A. Kluiver, M. Alieva, D. G. van Vuurden, Ellen J. Wehrens, Anne C. Rios
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Oncology
Subjects:
diffuse intrinsic pontine glioma (DIPG)
invasion
driver mutations
tumor subclones
microenvironment
therapeutic targeting
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00092/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.00092/full

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