Zerumbone, a Bioactive Sesquiterpene, Ameliorates Diabetes-Induced Retinal Microvascular Damage through Inhibition of Phospho-p38 Mitogen-Activated Protein Kinase and Nuclear Factor-κB Pathways

Zerumbone ameliorates retinal damage by blocking advanced glycation end products and their receptor system in streptozotocin-diabetic rats. Because of the multiple factors involved in diabetic retinopathy (DR) etiology, the mechanisms of zerumbone that are mainly responsible for its ameliorative eff...

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Bibliographic Details
Main Authors: Wayne Young Liu, Thing-Fong Tzeng, I-Min Liu
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/12/1708