Design, synthesis of novel lipids as chemical permeation enhancers and development of nanoparticle system for transdermal drug delivery.

Design, synthesis of novel lipids as chemical permeation enhancers and development of nanoparticle system for transdermal drug delivery.

In the present study, we designed and developed novel lipids that include (Z)-1-(Octadec-9-en-1-yl)-pyrrolidine (Cy5T), 1, 1-Di-((Z)-octadec-9-en-1-yl)pyrrolidin-1-ium iodide (Cy5), (Z)-1-(Octadec-9-en-1-yl)-piperidine (Cy6T), and 1, 1-Di-((Z)-octadec-9-en-1-yl) piperidin-1-ium iodide (Cy6) to enhan...

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Bibliographic Details
Main Authors: Srujan Marepally, Cedar H A Boakye, Punit P Shah, Jagan Reddy Etukala, Adithi Vemuri, Mandip Singh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3861410?pdf=render

Internet

http://europepmc.org/articles/PMC3861410?pdf=render

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