A non-VH1-69 heterosubtypic neutralizing human monoclonal antibody protects mice against H1N1 and H5N1 viruses.

A non-VH1-69 heterosubtypic neutralizing human monoclonal antibody protects mice against H1N1 and H5N1 viruses.

Influenza viruses are among the most important human pathogens and are responsible for annual epidemics and sporadic, potentially devastating pandemics. The humoral immune response plays an important role in the defense against these viruses, providing protection mainly by producing antibodies direc...

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Bibliographic Details
Main Authors: Donata De Marco, Nicola Clementi, Nicasio Mancini, Laura Solforosi, Guisella J Moreno, Xiangjie Sun, Terrence M Tumpey, Larisa V Gubareva, Vasiliy Mishin, Massimo Clementi, Roberto Burioni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3319592?pdf=render

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http://europepmc.org/articles/PMC3319592?pdf=render

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