Low oxygen saturation during sleep reduces CD1D and RAB20 expressions that are reversed by CPAP therapy

Low oxygen saturation during sleep reduces CD1D and RAB20 expressions that are reversed by CPAP therapy

Background: Sleep Disordered Breathing (SDB) is associated with a wide range of pathophysiological changes due, in part, to hypoxemia during sleep. We sought to identify gene transcription associations with measures of SDB and hypoxemia during sleep, and study their response to treatment. Methods: I...

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Bibliographic Details
Main Authors: Tamar Sofer, Ruitong Li, Roby Joehanes, Honghuang Lin, Adam C. Gower, Heming Wang, Nuzulul Kurniansyah, Brian E. Cade, Jiwon Lee, Stephanie Williams, Reena Mehra, Sanjay R. Patel, Stuart F. Quan, Yongmei Liu, Jerome I. Rotter, Stephen S. Rich, Avrum Spira, Daniel Levy, Sina A. Gharib, Susan Redline, Daniel J. Gottlieb
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:EBioMedicine
Subjects:
Gene expression
Obstructive Sleep Apnea
Hypoxemia
Online Access:http://www.sciencedirect.com/science/article/pii/S235239642030178X

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http://www.sciencedirect.com/science/article/pii/S235239642030178X

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