Measuring multiple parameters of CD8+ tumor-infiltrating lymphocytes in human cancers by image analysis

Measuring multiple parameters of CD8+ tumor-infiltrating lymphocytes in human cancers by image analysis

Abstract Background Immuno-oncology and cancer immunotherapies are areas of intense research. The numbers and locations of CD8+ tumor-infiltrating lymphocytes (TILs) are important measures of the immune response to cancer with prognostic, pharmacodynamic, and predictive potential. We describe the de...

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Bibliographic Details
Main Authors: Keith E. Steele, Tze Heng Tan, René Korn, Karma Dacosta, Charles Brown, Michael Kuziora, Johannes Zimmermann, Brian Laffin, Moritz Widmaier, Lorenz Rognoni, Ruben Cardenes, Katrin Schneider, Anmarie Boutrin, Philip Martin, Jiping Zha, Tobias Wiestler
Format: Article
Language:English
Published: BMJ Publishing Group 2018-03-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Cancer immunotherapy
Tumor microenvironment
CD8
Image analysis
Immuno-oncology
Tumor-infiltrating lymphocytes
Online Access:http://link.springer.com/article/10.1186/s40425-018-0326-x

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http://link.springer.com/article/10.1186/s40425-018-0326-x

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