Subgroup analyses in confirmatory clinical trials: time to be specific about their purposes

Subgroup analyses in confirmatory clinical trials: time to be specific about their purposes

Abstract Background It is well recognized that treatment effects may not be homogeneous across the study population. Subgroup analyses constitute a fundamental step in the assessment of evidence from confirmatory (Phase III) clinical trials, where conclusions for the overall study population might n...

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Bibliographic Details
Main Authors: Julien Tanniou, Ingeborg van der Tweel, Steven Teerenstra, Kit C. B. Roes
Format: Article
Language:English
Published: BMC 2016-02-01
Series:BMC Medical Research Methodology
Subjects:
Clinical trials
Subgroups
Subgroup analysis
Online Access:http://link.springer.com/article/10.1186/s12874-016-0122-6

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http://link.springer.com/article/10.1186/s12874-016-0122-6

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